Tracazolate hydrochloride

CAS No. 1135210-68-2

Tracazolate hydrochloride ( Tracazolate (hydrochloride) )

Catalog No. M27728 CAS No. 1135210-68-2

Tracazolate hydrochloride is a modulator of the GABAA receptor with anxiolytic and anticonvulsant activity.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 32 Get Quote
5MG 53 Get Quote
10MG 86 Get Quote
25MG 177 Get Quote
50MG 295 Get Quote
100MG 444 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    Tracazolate hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    Tracazolate hydrochloride is a modulator of the GABAA receptor with anxiolytic and anticonvulsant activity.
  • Description
    Tracazolate hydrochloride is a modulator of the GABAA receptor with anxiolytic and anticonvulsant activity. Tracazolate hydrochloride potentiates α1β1γ2s and α1β3γ2 with EC50s of 13.2 μM and 1.5 μM.(In Vitro):Tracazolate hydrochloride (10 μM) enhanced the sensitivity of α1β2δ-containing GABAA receptors and increased the maximum current amplitude in oocytes . Tracazolate hydrochloride inhibited α1β1ε, α1β3ε, α1β3, and α6β3γ with EC50s of 4.0 μM, 1.2 μM, 2.7 μM, and 1.1 μM. Tracazolate hydrochloride interacted with γ-aminobutyric acid GABAA receptors, adenosine receptors, and phosphodiesterases .
  • Synonyms
    Tracazolate (hydrochloride)
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1135210-68-2
  • Formula Weight
    340.9
  • Molecular Formula
    C16H25ClN4O2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    Cl.CCCCNc1c(C(=O)OCC)c(C)nc2n(CC)ncc12
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.King HL Jr, Dyar RE, Wilken DR. Ketopantoyl lactone and ketopantoic acid reductases. Characterization of the reactions and purification of two forms of ketopantoyl lactone reductase. J Biol Chem. 1974 Aug 10;249(15):4689-95.
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