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Tracazolate hydrochloride

CAS No. 1135210-68-2

Tracazolate hydrochloride ( Tracazolate (hydrochloride) )

Catalog No. M27728 CAS No. 1135210-68-2

Tracazolate hydrochloride is a modulator of the GABAA receptor with anxiolytic and anticonvulsant activity.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Tracazolate hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    Tracazolate hydrochloride is a modulator of the GABAA receptor with anxiolytic and anticonvulsant activity.
  • Description
    Tracazolate hydrochloride is a modulator of the GABAA receptor with anxiolytic and anticonvulsant activity. Tracazolate hydrochloride potentiates α1β1γ2s and α1β3γ2 with EC50s of 13.2 μM and 1.5 μM.(In Vitro):Tracazolate hydrochloride (10 μM) enhanced the sensitivity of α1β2δ-containing GABAA receptors and increased the maximum current amplitude in oocytes . Tracazolate hydrochloride inhibited α1β1ε, α1β3ε, α1β3, and α6β3γ with EC50s of 4.0 μM, 1.2 μM, 2.7 μM, and 1.1 μM. Tracazolate hydrochloride interacted with γ-aminobutyric acid GABAA receptors, adenosine receptors, and phosphodiesterases .
  • Synonyms
    Tracazolate (hydrochloride)
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1135210-68-2
  • Formula Weight
    340.9
  • Molecular Formula
    C16H25ClN4O2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    Cl.CCCCNc1c(C(=O)OCC)c(C)nc2n(CC)ncc12
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.King HL Jr, Dyar RE, Wilken DR. Ketopantoyl lactone and ketopantoic acid reductases. Characterization of the reactions and purification of two forms of ketopantoyl lactone reductase. J Biol Chem. 1974 Aug 10;249(15):4689-95.
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